【单选题】
(1)Which of the following parts of knowledge of drugs should be included in pharmacology?___
A. The effects of drugs on man
B. The correlation of biological activity with chemical structure
C. The history, source, physical and chemical properties, compounding, biochemical and physiologicaleffects, mechanisms of action, absorption, distrilbution, biotransformation and excretion.
D. The prevention, recognition, and treatment of drug poisonings
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答案
C
解析
暂无解析
相关试题
【单选题】
(2)Which of the following is what a clinician is primarily interested in according to the text?___
A. Drugs which can be reasonably limited to those aspects that provide the basis for their rational clinical use
B. Chemical agents that are not used in therapy but are commonly responsible for household and industrial poisoning as well as environmental pollution
C. Drugs which are useful in the prevention,diagnosis and treatment of human disease,or in the prevention of pregnancy.
D. rugs which are useful in the prevention, diagnosis and treatment of human disease, or in the prevention of pregnancy.
【单选题】
(3)Why was the physician not interested in pharmacognosy?___
A. He didn't have to select the proper plants for his prescription
B. He had a broad botanical knowledge
C. Fewer drugs were obtained from natural sources
D. Natural drugs had little difference with synthetic ones
【单选题】
(4)Which of the following is the best way of studying pharmacology for medical students and practitioners?___
A. to have a broad botanical knowledge
B. to select a plant and its preparation
C. to have the ability to purify natural plants
D. to have curiosity that stimulates them to learn about sources of drugs
【单选题】
(5)What are the tasks related to medicines almost complete!y delegated to the pharmacists now?___
A. the physical and chemical properties of medicines
B. the preparing, compounding, and dispensing of medicines
C. dosage forms of medicines available
D. the therapeutic and other uses of medicines
【单选题】
(6) What is a main unique aspect of pharmacodynamics?___
A. Pharmacodynamics is an experimental medical science
B. Pharmacodynamics is focused on the characteristics of drugs
C. Pharmacodynamics borrows freely from both the subject matter and the experimenta techniques of physiology, biochemistry, microbiology, genetics and pathology
D. Pharmacodynamics correlates the entire field of preclinical medicine
【单选题】
7) What time of history does pharmacodynamics date back to?___
A. the second half of the seventeenth century
B. the second half of the eighteenth century
C. the second half of the nineteenth century
D. the second half of the twentieth century
【单选题】
8)What does the research on pharmacodynamics focus on?___
A. study of clinical effect of drugs
B. study of the process of drugs in the body
C. study of the effect and the mechanism of drugs on the body
D. study of the correlation of the actions and effects of drugs with their chemical structure
【单选题】
(9)Which of the following is true when drugs are selected?___
A. It has to be based in part on legal reasons.
B. It has to be based in part on ethical reasons.
C. It has to be based in part on the pharmacological evaluation in man
D. It has to be based in part on the pharmacological evaluation in animals
【单选题】
(10)Why are chemotherapeutic agents useful in therapy?___
A. They stimulate or depress biochemical or physiological function in man in a sufficiently reproducible manner to provide relief of symptoms or, ideally, to alter favorably the course of disease
B. They can produce desired effects with only tolerable undesired effects
C. They have only minimal effects on man but can destroy or eliminate parasites
D. The selectivity of their effects is one of their most important characteristics
【单选题】
1)H. Mario Geysen initially used parallel synthesis as a quick way to identify which small_____ of any given large protein bound to an antibody.___
A. division
B. pieces
C. part
D. fragment
【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
【单选题】
3)The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
(2)Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
(7)Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
A. 对
B. 错
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
A. 对
B. 错
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
A. 对
B. 错
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
A. 对
B. 错
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
A. 对
B. 错
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
A. 对
B. 错
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
A. 对
B. 错
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
A. 对
B. 错
【判断题】
(3) As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
A. 对
B. 错
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
A. 对
B. 错
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
A. 对
B. 错
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___0247.用人单位应当对作业场所的应急设施进行经常性的( ),定期检测其性能和效果,确保其处于良好运行状态。
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【单选题】
___0263.申请取得剧毒化学品购买许可证时需向所在地县级人民政府公安机关提交的材料不包括( )。
A. 营业执照或者法人证书(登记证书)的复印件
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A. 3个月
B. 6个月
C. 1年
D. 2年
【单选题】
___0265.剧毒化学品、易制爆危险化学品的销售企业、购买单位应当在销售、购买后( )日内,将所销售、购买的剧毒化学品、易制爆危险化学品的品种、数量以及流向信息报所在地县级人民政府公安机关备案,并输入计算机系统。
A. 3
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C. 7
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【单选题】
___0268.运输危险化学品,应当根据危险化学品的危险特性采取相应的安全防护措施,并配备必要的防护用品和( )。
A. 灭火器
B. 通信设备
C. 应急救援器材
D. 照明设备
【单选题】
___0270.开启危险化学品金属容器时,应当使用( )扳手等工具,禁止使用( )工具操作。
A. 铜质;黑色金属
B. 铁质;有色金属
C. 铜制;放射性金属
D. 铜质;贵金属
【单选题】
___0271.下列说法错误的是( )。
A. 托运危险化学品的,托运人应当向承运人说明所托运的危险化学品的种类、数量、危险特性以及发生危险情况的应急处置措施
B. 运输危险化学品需要添加抑制剂或者稳定剂的,应当由承运人添加
C. 托运人不得在托运的普通货物中夹带危险化学品,不得将危险化学品匿报或者谎报为普通货物托运
D. 任何单位和个人不得交寄危险化学品或者在邮件、快件内夹带危险化学品
【单选题】
___0272.国家实行危险化学品登记制度,为危险化学品安全管理以及危险化学品事故预防和应急救援提供( )支持。
A. 信息、检测
B. 技术、检测
C. 信息、监测
D. 技术、信息
【单选题】
___0273.危险化学品生产企业、进口企业,应当向国务院( )负责危险化学品登记的机构办理危险化学品登记。
A. 质检部门
B. 环境保护部门
C. 安全生产监督管理部门
D. 公安部门
【单选题】
___0274.危险化学品单位应当制定本单位危险化学品事故应急预案,配备应急救援人员和必要的应急救援器材、设备,并( )。
A. 实施监督
B. 签订安全责任书
C. 定期组织应急救援演练
D. 组织员工进行应急培训
【单选题】
___0275.安全技术说明书每( )年更换一次。在此期间若发现新的危害特性,在有关信息发布后的( )年内,生产单位必须相应修改安全技术说明书,并提供给经营、运输、贮存和使用单位。
A. 六;半
B. 六;一
C. 五;半
D. 五;一
【单选题】
___0278.危险化学品使用单位应按国家有关规定清除( )和清洗盛装危险化学品的( )。
A. 化学废料;废旧容器
B. 化学废料;废旧仓库
C. 化学原料;废旧容器
D. 化学原料;废旧仓库
【单选题】
___0279.危险化学品生产企业申请安全生产许可证的条件不包括( )。
A. 生产区与非生产区混合设置
B. 涉及危险化工工艺的大型化工装置装设紧急停车系统
C. 涉及易燃易爆化学品的场所装设易燃易爆化学品泄漏报警等安全设施
D. 企业应当有相应的职业危害防护设施
【单选题】
___0281.运输剧毒化学品时,应事先依法取得( ),按指定路线、时间、速度行驶,并设专人押运,防止被盗、丢失。
A. 剧毒化学品公路运输通行证
B. 剧毒化学品公路运输准运证
C. 剧毒化学品公路运输过境证
D. 剧毒化学品公路运输许可证
【单选题】
___0282.通过道路运输剧毒化学品的,托运人应当向( )县级人民政府公安机关申请剧毒化学品道路运输通行证。
A. 运输始发地
B. 运输始发地或者目的地
C. 运输始发地和目的地
D. 目的地
【单选题】
___0283.危险化学品单位( )对本单位的重大危险源安全管理工作负责,并保证重大危险源安全生产所必需的安全投入。
A. 法定代表人
B. 主要负责人
C. 安全管理人员
D. 从业人员
【单选题】
___0284.危险化学品单位应对本单位的危险化学品生产、经营、储存和使用装置、设施或者场所进行重大危险源辨识,并记录辨识( )。
A. 过程与结果
B. 分析原因
C. 全过程
D. 危害因素