【单选题】
2)Chemists often start a combinatorial synthesis by attaching the first set of building blocks_____ to microscopic beads made of polystyrene.___
A. solid
B. inert
C. soft
D. active
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答案
B
解析
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相关试题
【单选题】
3）The chemical reactions required to link compounds to the beads and later to detach them____ to the synthesis proces.___
A. induce complications
B. make easy
C. introduce complications
D. introduce easy
【单选题】
4)In a parallel synthesis, all the products are_____ separately in their own reaction vessels.___
A. combined
B. assembled
C. joined
D. assorted
【单选题】
(5)In many laboratories today, robots assist with the routine work of parallel synthesis, such as small___ amounts of reactive molecules into the appropriate wells.___
A. sending
B. transporting
C. delivering
D. giving
【单选题】
(6)Scientists can pull out from the mixture the beads that bear biologically active molecules and then,using sensitive detection techniques,___ the molecular makeup of the compound attached.___
A. determine
B. make sure
C. find
D. search
【单选题】
(7)Most pharmaceutical companies today continue to___ parallel synthesis. Which of the following is not appropriate to be filled in the blank?___
A. count in
B. count on
C. depend on
D. rely on
【单选题】
(8)Once they identify a promising substance, they___ make many one-at-a-time modifications to the structure.___
A. laboriously
B. hardly
C. easy
D. effectively
【单选题】
(9)Often these procedures yield a compound having acceptable___ and safety.___
A. strength
B. effect
C. potency
D. effort
【单选题】
10)In many laboratories today, robots___ the routine work of parallel synthesis.___
A. help
B. assist with
C. assist in
D. assist to
【单选题】
(1)Pharmaceutics is an interdisciplinary subject involving___
A. formulation, manufacturing, physical pharmacy, and biopharmaceutics
B. manufacturing
C. physical pharmacy
D. biopharmaceutics
【单选题】
（2）Formulation is about the design, development and evaluation of dosage forms,___
A. discovery of novel drugs
B. analytical methods
C. drug delivery systems and manufacturing process
D. dosing regimen
【单选题】
(3)Biopharmaceutics mainly studies the in vivo process of drugs and metabolites in humans, animals and tissue culture, which specifically involves___
A. absorption and distribution
B. absorption, distribution, metabolism, and excretion
C. metabolism and excretion
D. absorption and excretion
【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
A. 对
B. 错
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
A. 对
B. 错
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
A. 对
B. 错
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
A. 对
B. 错
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
A. 对
B. 错
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
A. 对
B. 错
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
A. 对
B. 错
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
A. 对
B. 错
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
A. 对
B. 错
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
A. 对
B. 错
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
A. 对
B. 错
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
A. 对
B. 错
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
A. 对
B. 错
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
A. 对
B. 错
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
A. 对
B. 错
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
A. 对
B. 错
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
A. 对
B. 错
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
A. 对
B. 错
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
A. 对
B. 错
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
A. 对
B. 错
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
A. 对
B. 错
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
A. 对
B. 错
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关于社会主义初级阶段的问题，下列判断不正确的是___。
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新民主主义的经济纲领内容有___。
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D. 台、港、澳是中国不可分割的一部分
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邓小平同志说，“在改革中，我们始终坚持两条根本原则”。这两条原则是指___。
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C. 计划调节和市场调节相结合
D. 以按劳分配为主体
【多选题】
1959年底至1960年初，毛泽东在阅读苏联《政治经济学（教科书）》时，认为社会主义社会的发展阶段有___。
A. 社会主义高级阶段
B. 社会主义初级阶段
C. 比较发达的社会主义
D. 不发达的社会主义
【多选题】
毛泽东思想的科学涵义具体表现为___。
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B. 是马克思列宁主义在中国的运用和发展
C. 是被实践证明了的关于中国革命和建设的正确理论原则和经验总结
D. 是中国共产党集体智慧的结晶
【多选题】
毛泽东认为，充分调动一切积极因素，尽可能地克服消极因素，并且努力化消极因素为积极因素，这是社会主义事业前进的需要。这里讲的积极因素与消极因素，包括___。
A. 社会主义的因素和资本主义的因素
B. 国内的因素和国外的因素
C. 党内的因素和党外的因素
D. 直接的因素和间接的因素
【多选题】
我国对资本主义工商业的改造的一些具体办法是___。
A. 国家有偿地将私营企业改变为国营企业
B. 由国家一次性支付一笔巨额补偿资金
C. 让资本家在一定年限内从企业经营中获取一部分利润
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【多选题】
党的十三大召开前夕，邓小平强调指出：“社会主义本身是共产主义的初级阶段，而我们中国又处在社会主义的初级阶段，就是不发达的阶段，一切都要从这个实际出发，根据这个实际来制订规划。”这一论述___。
A. 为党的十三大的决策提供了重要理论基础
B. 首次系统阐述了社会主义初级阶段理论
C. 首次把社会主义初级阶段作为事关全局的基本国情加以把握
D. 首次对社会主义发展阶段进行了划分
【多选题】
“三个代表”重要思想的集中概括是中国共产党必须___。
A. 始终代表中国先进生产力的发展要求
B. 始终代表中国最广大人民的根本利益
C. 始终代表中国先进文化的前进方向
D. 始终代表中国社会历史发展的潮流
【多选题】
中国的红色政权能够存在和发展的原因是___。
A. 中国是一个政治经济发展极不平衡的半殖民地半封建的大国
B. 相当力量的正式红军的存在和党的领导
C. 有良好的群众基础
D. 中国革命形势的继续向前发展
【多选题】
新民主主义革命的经济纲领的内容是___。
A. 没收封建地主阶级的土地归农民所有
B. 没收官僚资本归新民主主义国家所有
C. 没收官僚资本归社会主义国家所有
D. 保护民族工商业
【多选题】
关于新民主主义社会性质，正确的结论有___。
A. 是一个独立的社会形态
B. 是属于社会主义体系的过渡性的社会
C. 是一个既有社会主义因素又有非社会主义因素的过渡性社会
D. 是一个社会主义因素起决定作用，必然向社会主义过渡的社会
【多选题】
“三个代表”重要思想的核心观点是___。
A. 中国共产党始终代表中国先进生产力的发展要求
B. 中国共产党始终代表中国先进文化的前进方向
C. 中国共产党始终代表中国先进科学技术发展水平
D. 中国共产党始终代表中国最广大人民的根本利益
【多选题】
毛泽东思想的科学涵义具体表现为___。
A. 是马克思列宁主义民族化的优秀典型
B. 是马克思列宁主义在中国的运用和发展
C. 是被实践证明了的关于中国革命和建设的正确理论原则和经验总结
D. 是中国共产党集体智慧的结晶
【多选题】
新民主主义革命与社会主义革命的关系是___。
A. 新民主主义革命是社会主义革命的必要准备
B. 社会主义革命是新民主主义革命的必然趋势
C. 两者可以同时进行，“毕其功于一役”
D. “二次革命论”，中间容许资产阶级专政
【多选题】
邓小平指出“计划经济不等于社会主义，资本主义也有计划；市场经济不等于资本主义，社会主义也有市场。”这一论断表明___。
A. 计划和市场都是经济手段
B. 计划经济和市场经济没有本质区别
C. 计划与市场的多少不是社会主义与资本主义的本质区别
D. 社会主义以计划经济为主，资本主义以市场经济为主
【多选题】
在第一次国内革命战争时期，毛泽东运用马克思主义阶级分析法撰写的___等著作，分析了中国社会各阶级在革命中的地位和作用，提出了中国新民主主义革命的基本思想。
A. 《井冈山的斗争》
B. 《中国社会各阶级的分析》
C. 《中国的红色政权为什么能够存在？》
D. 《湖南农民运动考察报告》
