【单选题】
(4)Regarding the definition of bioavailability(BA), BA is related to___
A. total plasma drug concentration only
B. unbound drug concentration in the plasma
C. unbound drug concentration at the target site
D. total plasma drug concentration, and the administered drug dose
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答案
D
解析
暂无解析
相关试题
【单选题】
(5)Plasma drug concentration is affected by following factors such as___
A. rate of absorption
B. rate and extent of distribution
C. rate ofeli Imination
D. all ofabove
【单选题】
6)Which of the following routes of administration will involve the absorption of drugs?___
A. i.v.injection
B. i.v.infusion
C. Subcutaneous injection, transdermal and oral
D. None of above
【单选题】
（7）Which of the following factors may influence the time course of a drug in the plasma and hence at its site of action?___
A. Food
B. Disease state
C. Route of administration
D. All of above
【单选题】
(8)Please identify the potential biological barriers for an orally administered tablet to be absorbed into the systemic circulation___
A. Sk d dermis
B. Gastrointestinal epithelium
C. Oral mucosal membrane
D. All of above
【单选题】
(9) Given the same administration dose, which of the following will likely result in varying bioavailabilities for the same drug administered to the same person? ___
A. tablets (p.o. )vs. solutions(p0.)
B. solutions for injection(i v )vs oral solutions(p0.)
C. coated tablets (p.0. )vs hard gelatin capsules(p0.)
D. All ofabove
【单选题】
(10)Which of the following statements is true?___
A. Bioavailability is only related to the administered dose and the total drug concentration in the blood circulation.
B. Plasma protein binding does not affect the bioavailability of a specific drug.
C. A given drug in different dosage forms may show differences in bioavailability if given by the same route.
D. Biopharmaceutical studies do not involve animal experiment.
【判断题】
Much of our present physiological knowledge has been found from the experiments and studies on human beings.
A. 对
B. 错
【判断题】
Living cells break down glucose and fats to provide energy for other activities, which is called.
A. 对
B. 错
【判断题】
The right atriapumps deoxygenated blood to the lungs where it absorbs oxygen from the air.
A. 对
B. 错
【判断题】
The nervous system uses electrical signals to transmit information very rapidly to specific cells.
A. 对
B. 错
【判断题】
With the level of sodium increasing extracelular fruid. the cardiac muscle cells become too excitable and may contract.
A. 对
B. 错
【判断题】
A negative feedback loop is a control system that acts to maintain the level of some variables within a given range following a disturbance
A. 对
B. 错
【判断题】
(1)Pharmacodynamics, which is concerned with the study of the biochemical and physiological effects of drugs and their mechanisms of action, Is an experimental medical science.
A. 对
B. 错
【判断题】
2)It's unreasonable for a physician to be interested mainly in the effects of drugs on human beings, for the pharmacological evaluation of drugs in them may be limited due to technical, legal, and ethical reasons.
A. 对
B. 错
【判断题】
（3） As the effects of drugs are often characterized by significant interspecies variation and may be further modified by disease, clinical pharmacology has never been efibrasized.
A. 对
B. 错
【判断题】
The physician is not interested in drugs that are useful in the prevention,diagnosis,and treatment of human disease, but in chemical agents that are commonly responsible for household and industrial poisoning as well as environmental pollution.
A. 对
B. 错
【判断题】
(5)A drug is said to be useful in therapy if it has the ability to produce its desired effects with only tolerable undesired effects.
A. 对
B. 错
【判断题】
(6)Toxicology deals not only with drugs used in therapy but also with many other chemicals that may be responsible for household, environmental, or industrial intoxication.
A. 对
B. 错
【判断题】
1)With the more efficient screening tests and burgeoning knowledge about how a molecules biological activities are likely to be changed, the traditional approach of discovering new drugs has been improved.
A. 对
B. 错
【判断题】
2)With the parallel synthesis used to identify which small segment of any given large protein would bind to an antibody, Mario Geysen generated a variety of short protein fragments by combining multiple amino acids in different permutations.
A. 对
B. 错
【判断题】
)A parallel synthesis and a split-and-mix synthesis are different in that in a split-and-mix synthesis, all the products are assembled separately n their respective reaction vessels.
A. 对
B. 错
【判断题】
4) In many laboratories, robots are used in the routine work of parallel synthesis to deliver small amounts of reactive molecules into appropriate wells, thus making the process more accurate and less tedious.
A. 对
B. 错
【判断题】
5) In a parallel synthesis, each compound remains in its own container; while in a split-and-min synthesis, the related ce mpounds are mixed up in the same reaction vessel.
A. 对
B. 错
【判断题】
6)In order to solve the difficulties of identifying the compounds made in a parallel synthesis scientists pull out from the mixture the beads that bear biologically active molecules and determine the molecular makeup o d attached.
A. 对
B. 错
【判断题】
1)The concentration of a drug in whole plasma is the most accurate index of the drug concentration at the site（s） of action.
A. 对
B. 错
【判断题】
(2)It is difficult to measure the total concentration of both unbound and bound drug in total plasma.
A. 对
B. 错
【判断题】
(3)The clinical effect of a drug is assumed to be directly related to the plasma drug concentration.
A. 对
B. 错
【判断题】
(4) Systemically acting drugs administered by all routes involve the absorption of drug from the place of administration into the blood.
A. 对
B. 错
【判断题】
5)Bioavailability of a drug indicates whether a therapeutically effective concentration is achieved at the site(s)of action of that drug.
A. 对
B. 错
【判断题】
(6)Prodrugs are not therapeutically effective unless they are changed into therapeutically active forms before or after reaching the systemic circulation
A. 对
B. 错
【单选题】
（3）生物圈的范围为___
A. 大气圈、水圈和岩石圈的全部
B. 大气圈和水圈的全部、岩石圈的上部
C. 大气圈的底部、水圈和岩石圈的全部
D. 大气圈的底部、水圈的全部和岩石圈的上部
【单选题】
（8）地球的表面积约为5.1亿平方千米，表面起伏不平，凸出来的地方成为陆地和山脉，而大片大片下凹的部分经过亿万年的积累，被液态海水所淹没而变成了海洋，海洋面积占地球表面积的近___。
A. 2％
B. 51%
C. 71%
D. 91%
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(B737ng)737NG发电机脱开控制和737-3/4/5有什么不同？___
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(B737ng)P5-13电源面板上有信息BAT CHG INOP I。其中字母I代表？___
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B. 没特别意思，不须按FIM排故即可
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(B737ng)start converter unit (SCU)的作用是___
A. 在APU起动过程中直接控制起动发电机来带动APU起动，和ECU没关系
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C. 在APU起动过程中，受ECU控制来监控起动发电机来带动APU起动
D. B & C对
【单选题】
(B737ng)采用恒速传动装置的发电机若频率负载特性不一致___
A. 不能并联
B. 可以并联但有功负载不相等
C. 可以并联但并联后电压不相等
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【单选题】
(B737ng)当“BUS XFR”电门放于AUTO位，那些控制有自动转换功能？___
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(B737ng)当给飞机接入外部直流电源时，应：___
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B. B. 断开外部直流跳开关
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(B737ng)当外电源接头面板上的“未使用”和“连接”灯亮时表示外电源:___
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C. 插头接触正常,外电源没有被使用
D. 以上答案都不对
【单选题】
(B737ng)电源面板P5-13的TR灯亮是代表___
A. 地面任一个TRU故障.
B. 空中任所有TRU故障
C. 空中TRU1或空中TRU2和TRU3都故障
D. 以上都有可能
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(B737ng)电源系统“TR UNIT”灯亮，可能原因为：___
A. 空中，TRU2故障，其它正常
B. 地面，仅当TRU1，2，3同时都发生了故障
C. 空中，TRU1故障，其它正常
D. 空中，TRU3故障,其它正常
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(B737ng)电源系统的“ELEC”灯亮的原因是：___
A. 交流系统发生故障
B. 交流和DC系统同时发生故障
C. BPCU发生故障
D. DC系统或备份电源系统故障
【单选题】
(B737ng)电源系统的“STBY PWR OFF”灯亮，则___
A. AC系统故障
B. 直流系统故障
C. AC和DC同时发生故障
D. AC、DC备分汇流条和BAT BUS 任一无电
【单选题】
(B737ng)电源系统的“TR UNIT”灯亮，可能原因是：___
A. 空中，TRU2故障，其它正常
B. 地面，仅当TRU1，2，3同时都发生了故障
C. 空中，TRU3故障,其它正常
D. 空中，TRU1故障，其它正常
【单选题】
(B737ng)飞机交流电源系统向汇流条提供___
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【单选题】
(B737ng)关于standby power control unit (SPCU)说法正确的是___
A. 737-3/4/5和737NG都有
B. 装在驾驶舱P18板内
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D. 主要作用是控制静变流机的工作
【单选题】
(B737ng)关于standby power control unit (SPCU)装在___
A. 装在驾驶舱P18板内
B. 装在驾驶舱P6板内
C. 装在前电子舱
D. 装在主电子舱
【单选题】
(B737ng)关于start converter unit (SCU)的作用正确的是___
A. 调节APU起动发电机的输出
B. 在APU起动过程中直接控制起动发电机来带动APU起动，和ECU没关系
C. 在APU起动过程中，受ECU控制来监控起动发电机来带动APU起动
D. A&C对
