【多选题】
哪些属于非血液学不良反应()。
A. 中性粒细胞减少症
B. 胃肠道异常
C. 皮疹
D. 肌痛
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答案
BCD
解析
暂无解析
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以下达希纳主要信息包括( )。
A. 达希纳是专为CML设计的二代TKI,强效精准抑制BCR-ABL
B. 达希纳更快获得更深缓解,减少疾病进展
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【多选题】
以下哪个说法是正确的是()。
A. 所有TKI由于抑制野生型Bcr-Abl,都会对心血管系统产生影响
B. 临床试验证实:达希纳治疗患者的心血管事件发生率与同年龄组普通人群相似
C. 所有进行TKI治疗的CML患者,都应该进行心血管风险因素的评估
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有研究推荐,晚期CML患者移植后为预防急性移植物抗宿主病(aGVHD),可接受()治疗。
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与伊马替尼相比格列卫,达希纳作为一线治疗的优势是()。
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早期的分子学反应(3个月时Bcr-Abl水平)与以下哪个长期预后相关?
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2013 ELN 推荐切换至二代TKI3个月时BCR-ABLIS ≤ 1% 被认为达到最佳反应。
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D.
【多选题】
2013版中国CML指南推荐:移植后3月起TKI治疗1年,预防复发。
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2016中国CML指南定义一线格列卫治疗失败的标准为,任何时间丧失CHR或CCyR或MMR,出现伊马替尼或其他TKI耐药性突变,出现Ph染色体基础上其他克隆性染色体异常。
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【多选题】
2016中国CML指南定义一线格列卫治疗失败的标准为12个月未达到CCyR。
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2016中国CML指南定义一线格列卫治疗失败的标准为3个月无任何CyR。
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【多选题】
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